When treating depression with antidepressants, a 10 – 12-week trial is necessary to achieve remission. The dose and the combination of medicine that gets you better, keeps you better and should be continued for maintenance therapy for at least one year. The most common antidepressant prescribed these days are Selective Serotonin Reuptake Inhibitors (SSRIs) like Paxil, Zoloft® and Prozac.
Most patients with depression will benefit from a combination of medications and psychotherapy. Cognitive behavioral therapy and interpersonal psychotherapy have been shown to be as efficacious as antidepressants in mild to moderate depression.
Cutting Edge Treatments
Ketamine IV infusions are being used with great success for hard-to-treat cases of depression. An intranasal formulation of esketamine (Spravato®) is also available now. The benefits of Ketamine can be felt by the patient within 24 hours and can reverse suicidal tendencies thereby buying the patient and therapist more time for appropriate interventions. Learn more about how ketamine can relieve depression.