An antidepressant knows as a selective serotonin reuptake inhibitor (SSRI) such as Paxil, Zoloft® or Prozac is effective for PTSD. The medication Prazosin has been found to be helpful in decreasing nightmares.
Ketamine IV infusions are now being used to treat PTSD. Unlike SSRIs which can take weeks to months to start working, a patient can feel the benefits of Ketamine within 24 hours.
Cognitive Processing Therapy (CPT): Patients learn skills to help them understand how trauma has changed their thoughts and feelings.
Prolonged Exposure Therapy (PET): Patient talks about his or her trauma repeatedly until the memories are no longer upsetting.
IV Ketamine Treatment for Post-Traumatic Stress Disorder – There have been many individual reports in the medical literature of patients improving with intravenous ketamine treatment. In two phases of a study at Mount Sinai, ketamine was associated with substantial reduction in PTSD symptom severity. Ketamine also had an antidepressant effect, and this also was seen most strongly after one day. Ketamine-related improvement in PTSD was independent of ketamine-esketamine-related improvement in depression.